The United States is a great big place, with plenty of amazing destinations, but these are by far the 15 best spring break destinations in the US. From Seattle Washington to Miami Florida, the US is a great big place and these are by far the best way to spend your Spring Break exploring and relaxing. You can enjoy the Space Needle in Seattle, hike the red rock formations in Sedona, explore the world famous bioluminescent bays in Puerto Rico, enjoy the hiking and empty Cannon Beach in Oregon. ou can’t go wrong with any of these 15 best spring break destinations, the US has so many amazing options, and this list will really help you narrow it down to the best fit for you.